Registered Nurse Salary in Indianapolis, IN
Registered Nurse salaries in Indianapolis range from $46,750 to $97,750 in 2026. The mid-level median is $65,875, which is 15% below the national average.
Junior (0-2 yrs)
$46,750 – $55,250
Median: $51,000 · per year
Mid-Level (3-5 yrs)
$59,500 – $72,250
Median: $65,875 · per year
Senior (6+ yrs)
$76,500 – $97,750
Median: $87,125 · per year
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5 years
Entry level20+ years
Estimated Registered Nurse Salary in Indianapolis, IN
Estimated†$68,000–$85,000/year
Median: $76,500 per year (adjusted for Indianapolis cost of living)
Junior
$51,000
0-2 yrs
Mid-Level
$65,875
3-5 yrs
Senior
$87,125
6+ yrs
Cost of Living in Indianapolis
Cost of Living Levellow
Population880K
Top IndustriesPharmaceuticals & Life Sciences, Healthcare, Logistics
vs National Average-15%
Top Employers in Indianapolis
Eli LillyAnthem (Elevance Health)SalesforceIndiana University HealthRolls-Royce North America
How Indianapolis Compares
| City | Mid-Level Median | Cost of Living |
|---|---|---|
| Indianapolis, IN | $65,875 | low |
| New York, NY | $112,375 | very high |
| Los Angeles, CA | $112,375 | very high |
| Chicago, IL | $93,000 | high |
| Houston, TX | $77,500 | moderate |
| Phoenix, AZ | $77,500 | moderate |