Registered Nurse Salary in Louisville, KY
Registered Nurse salaries in Louisville range from $46,750 to $97,750 in 2026. The mid-level median is $65,875, which is 15% below the national average.
Junior (0-2 yrs)
$46,750 – $55,250
Median: $51,000 · per year
Mid-Level (3-5 yrs)
$59,500 – $72,250
Median: $65,875 · per year
Senior (6+ yrs)
$76,500 – $97,750
Median: $87,125 · per year
Salary Calculator
Estimate your earning potential based on role, location, and experience.
5 years
Entry level20+ years
Estimated Registered Nurse Salary in Louisville, KY
Estimated†$68,000–$85,000/year
Median: $76,500 per year (adjusted for Louisville cost of living)
Junior
$51,000
0-2 yrs
Mid-Level
$65,875
3-5 yrs
Senior
$87,125
6+ yrs
Cost of Living in Louisville
Cost of Living Levellow
Population630K
Top IndustriesLogistics & Shipping, Healthcare & Insurance, Manufacturing
vs National Average-15%
Top Employers in Louisville
UPSHumanaGE AppliancesNorton HealthcareYum! Brands
How Louisville Compares
| City | Mid-Level Median | Cost of Living |
|---|---|---|
| Louisville, KY | $65,875 | low |
| New York, NY | $112,375 | very high |
| Los Angeles, CA | $112,375 | very high |
| Chicago, IL | $93,000 | high |
| Houston, TX | $77,500 | moderate |
| Phoenix, AZ | $77,500 | moderate |